When the opiate receptor relies on G protein coupling for signal transduction, this receptor was discovered to make use of arrestin activation for internalization of the receptor. If not, the receptor promoted no other signali… Read More

Elucidating the precise pharmacological mechanism of action (MOA) of naturally happening compounds is usually hard. While Tarselli et al. (60) formulated the first de novo artificial pathway to conolidine and showcased this na… Read More

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Elucidating the exact pharmacological mechanism of action (MOA) of naturally transpiring compounds might be tough. Whilst Tarselli et al. (60) developed the main de novo artificial pathway to conolidine and showcased this By n… Read More